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Research Publications

In Press | 2019 | 2018 | Publications before 2018


In Press

Wani, T.A.;  Pandith, S.A.; Gupta, A.P.; Chandra, S.; Sharma, N.; Lattoo, S.K. Molecular and functional characterization of two isoforms of chalcone synthase and their expression analysis in relation to flavonoid constituents in Grewia asiatica L . PLoS One, DOI:10.1371/journal.pone.0179155.
Rasool, R.U.; Nayak, D.; Chakraborty, S.; Faheem, M. M.; Rah, B.; Mahajan, P.; Gopinath, V.; Katoch, A.; Iqra, Z.; Yousuf, S. K. AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress. Oncogenesis, DOI:10.1038/oncsis.2017.41.
Dhar, N.; Razdan, S.; Rana, S.; Bhat, W.W.; Vishwakarma, R.A.; Lattoo, S.K. A decade of molecular understanding of withanolide biosynthesis and in vitro studies in Withania somnifera (L.) Dunal: Prospects and perspectives for pathway engineering. Frontiers in Plant Science, DOI: 10.3389/fpls.2015.01031.


Representative Publications During 2019

Awasthi, P.; Mahajan, V.; Jamwal, V.L.; Chouhan, R.; Kapoor, N.; Bedi, Y. S.; Gandhi, S.G. Characterization of the gene encoding 4-coumarate:CoA ligase in Coleus forskohlii. Journal of Plant Biochemistry and Biotechnology, 2019, 2, 203–210.


Representative Publications During 2018

Bharate, S.S.; Mignani, S.; Vishwakarma, R.A. Why Are the Majority of Active Compounds in the CNS Domain Natural Products? A Critical Analysis. Journal of Medicinal Chemistry, 2018, 13, 10345-10374.
Mudududdla, R.; Mohanakrishnan, D.; Bharate, S.S.; Vishwakarma, R.A.; Sahal, D.; Bharate, S.B. Orally Effective Aminoalkyl 10H-Indolo-[3,2-b]quinoline-11-carboxamide Kills the Malaria Parasite by Inhibiting Host Hemoglobin Uptake. ChemMedChem, 2018, 13, 2581-2598.
Thottacherry, J,J.;  Kosmalska, A.J.; Kumar, A.; Vishen, A.S.; Elosegui-Artola, A.; Pradhan, S.; Sharma, S.; Singh, P.P.; Guadamillas, M.C.; Chaudhary, N.; Vishwakarma, R.; Trepat, X.; Pozo, M.A.d.; Parton, R.G.; Rao, M.; Pullarkat, P.; Roca-Cusachs, P.; Mayor, S. Mechanochemical feedback control of dynamin independent endocytosis modulates membrane tension in adherent cells. Nature Communications, 2018, 9, 4217.
Bharate, S.B.; Kumar, V.; Jain, S.K.; Mintoo, N.J.; Guru, S.K.; Nuthakki, V.K.; Sharma, M.; Bharate, S.S, Gandhi, S.G.; Mondhe, D.M.; Bhushan, S.; Vishwakarma, R.A. Discovery and Preclinical Development of IIIM-290, an Orally Active Potent Cyclin-dependent Kinase Inhibitor. Journal of Medicinal Chemistry, 2018, 61, 1664-1687.
Bharate, S.S.; Kumar, V.; Singh, G.D.; Singh, A.; Gupta, M.; Singh, D.; Kumar, A.; Vishwakarma, R.A.; Bharate, S.B. Preclinical development of Crocus sativus based botanical lead IIIM-141 for Alzheimer's disease: Chemical standardization, efficacy, formulation development, pharmacokinetics and safety pharmacology. ACS Omega, 2018, 3, 9572−9585.
Gupta, M.; Wani, A.; U.l Ahsan, A.; Chopra, M.; Vishwakarma, R.A.; Singh, G.; Kumar, A. Soluble Aβ1-42 suppresses TNF-α and activates NLRP3 inflammasome in THP-1 macrophages. Cytokine, 2018, 11184-87.
Bhat, Z.S.; Rather, M. A.; Maqbool, M.; Ahmad ,Z.; Bhat, Z. S.; Ahmad, Z.; Yousuf, S. K.; Ul Lah, H.; Yousuf ,S. K.; Ara ,T. Synthesis and in vitro evaluation of substituted 3-cinnamoyl-4-hydroxy-pyran-2-one (CHP) in pursuit of new potential antituberculosis agents .MedChemComm, 2018, 9,1, 165-172.
Rasool, F.; Ahmed, A.; Hussain, N.; Mukherjee, D.; Rasool, F.; Ahmed, A.; Hussain, N.; Yousuf, S.K.; Mukherjee, D . One-Pot Regioselective and Stereoselective Synthesis of C-Glycosyl Amides from Glycals Using Vinyl Azides as Glycosyl Acceptors .Organic letters, 2018, 20,13, 4036-4039.
Saneja, A.; Arora, D.; Dubey, R.D.; Kumar, R.; Panda, A. K.; Gupta, P. N. CD44 targeted PLGA nanomedicines for cancer chemotherapy. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, 12147-58.
Sharma, V.; Sharma, N.; Arora, D.; Singamaneni, V.; Kumar, A.; Kushwaha, M.; Bhushan, S.; Jaglan, S.; Gupta, P. Valproic acid induces three novel cytotoxic secondary metabolites in Diaporthe sp., an endophytic fungus from Datura inoxia Mill. Bioorganic & medicinal chemistry letters, 2018, 28,12, 2217-2221.
Wani ,N. A.; Singh, G.; Shankar, S.; Sharma, A.; Katoch, M.; Rai, R. Corrigendum to “Short hybrid peptides incorporating β- and γ-amino acids as antimicrobial agents” [Peptides 97 (2017) 46-53]. Peptides, 2018, 10485.
Mignani, S.; Rodrigues, J.;  Tomas, H.;  Jalal , R.; Singh , P.P; Majoral , J.P.; Vishwakarma, R.A. Present drug-likeness filters in medicinal chemistry during the hit and lead optimization process: how far can they be simplified. Drug discovery today, 2018, 23,3, 605-615.
Kumar, S.; Bokolia, N.P.; Mehra, R.; Nargotra, A.; Sharma, S.; Singh, P.P.; Raina, D.; Khan, I. A. Screening of antitubercular compound library identifies novel ATP synthase inhibitors of Mycobacterium tuberculosis.Tuberculosis (Edinburgh, Scotland), 2018, 10856-63.
Saneja, A.; Kumar, R.; Panda, A. K.; Arora, D.; Jaglan, S.; Kumar, S. Recent advances in near-infrared light-responsive nanocarriers for cancer therapy. Drug discovery today, 2018, 23, 5, 1115-1125.
Gupta, N.; Qayum, A.; Singh, S.; Raina, A.; Shankar, R.; Gairola, S.; Sangwan, P. L. Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents. European journal of medicinal chemistry, 2018, 145511-523.
Gupta, S.; Khajuria ,V.; Ahsan, A. U.; Wani, A.; Nazir, L. A.; Sharma, S.; Ali, S. The amino analogue of β-boswellic acid efficiently attenuates the release of pro-inflammatory mediators than its parent compound through the suppression of NF-κB/IκBα signalling axis. Cytokine, 2018, 10793-104.
Joshi, P.; Sonawane, V.R.; Williams, I.S.;   McCann, G.J. P.; Gatchie, L.; Sharma, R.;  Satti, N.;  Chaudhuri, B.; Bharate, S.B. Identification of karanjin isolated from the Indian beech tree as a potent CYP1 enzyme inhibitor with cellular efficacy via screening of a natural product repository. MedChemComm, 2018, 9, 2, 371-382.
Dar, N.J.; Satti, N.K.; Dutt, P.; Hamid, A.; Ahmad, M. Attenuation of Glutamate-Induced Excitotoxicity by Withanolide-A in Neuron-Like Cells: Role for PI3K/Akt/MAPK Signaling Pathway. Molecular Neurobiology, 2018, 55, 4, 2725-2739.
Singh, V.P.; Yedukondalu, N.; Sharma, V.; Kushwaha, M.; Sharma, R.; Chaubey, A.; Kumar, A.; Singh, D.;  Vishwakarma, R.A. Lipovelutibols A–D: Cytotoxic Lipopeptaibols from the Himalayan Cold Habitat Fungus Trichoderma velutinum. Journal of Natural Products, 2018, 81, 2, 219–226.
Kushwaha, M.;  Jain, S.K.; Sharma, N.;  Abrol, V.; Jaglan, S.; Vishwakarma, R.A. Establishment of LCMS Based Platform for Discovery of Quorum Sensing Inhibitors: Signal Detection in Pseudomonas aeruginosa PAO1. ACS Chemical Biology, 2018, 13, 3, 657–665.
Kour, D.; Gupta, A.; Kapoor, K.K.; Gupta, V.K.; Rajnikant; Singh, D.; Das, P. Iodine–NH4OAc mediated regioselective synthesis of 2-aroyl-3-arylimidazo[1,2-a]pyridines from 1,3-diaryl-prop-2-en-1-ones. Organic & Biomolecular chemistry,2018, 16, 1330-1336.
Sharma, A.; Magotra, A.; Rath, S.K.; Wazir, P.; Nandi, U.; Koul, S.; Sangwan, P.L.; Gupta, A.P.; Singh, G. In-vitro and in-vivo pharmacokinetics of IS01957, p-coumaric acid derivative using a validated LC-ESI-MS/MS method in mice plasma. Journal of Pharmaceutical Investigation, 2018, 48, 5, 565–574.
Kumar, S.; Mehra, R.; Sharma, S.; Bokolia, N.P.; Raina, R.; Nargotra, A.; Singh, P.P.; Khan, I.A. Screening of antitubercular compound library identifies novel ATP synthase inhibitors of Mycobacterium tuberculosis. Tuberculosis, 2018, 108, 56-63.
Gupta, N.; Qayum, A.; Raina, A.; Shankar, R.; Gairola, S.; Singh, S.; Sangwan, P. L. Synthesis and biological evaluation of novel bavachinin analogs as anticancer agents. European Journal of Medicinal Chemistry, 2018, 145, 511-523.  
Rather, G.A.; Sharma, A.; Pandith, S.A.; Kaul, V.; Nandi, U.; Misra, P.; Lattoo, S.K. De novo transcriptome analyses reveals putative pathway genes involved in biosynthesis and regulation of camptothecin in Nothapodytes nimmoniana (Graham) Mabb. Plant Molecular Biology, 2018, 96, 197-215.



Publications before 2018

               Complete list of publications during 2017

               Complete list of publications during 2016

               Complete list of publications during 2015

               Complete list of publications during 2014

               Complete list of publications during 2013

               Complete list of publications during 2012

               Complete list of publications during 2011