CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM) was established in 1941 as a research and production centre, known as Drug Research Laboratory of Jammu and Kashmir State and was later taken over by Council of Scientific & Industrial Research (CSIR) of Govt. of India in December 1957 as Regional Research Laboratory, Jammu. In view of its core strength in natural products based drug discovery, the mandate of Institute was redefined in 2005 and its name changed to Indian Institute of Integrative Medicine (IIIM). The current mandate of IIIM is to discover new drugs and therapeutic approaches from Natural Products (plant and microbial origin), enabled by biotechnology, to develop technologies, drugs and products of high value for the national and international markets.

Fermentation Technology Division of CSIR-IIIM

The Fermentation Technology Division is well equipped with state-of-the-art fermentation facility from lab scale to pilot scale (5-4000 L capacity) including recent micro-processor controlled fermenters (5-500 L capacity) and matching down-stream processing facilities for bacterial, fungal and yeast based products. The facility is available for industrial scale production of novel bioactive products, biocatalysts, bio-transformed products for human health and enhanced agriculture crop yields through microbial fertilizer, biocides, metal gluconates and other applications. The Fermentation Technology Division is also involved in various consultancy projects and is helping Indian industries to scale up the processes. The main thrust areas of the division are:

  • Production
  • Process optimization
  • Scale up
  • Downstream processing
  • Purification
  • Characterization
  • Possible industrial applications
  • Exploitation of various bioactive molecules produced by microorganisms using fermentation


  • Fermentation process for the production of biopesticide and biofertilizer
  • Fermentation process for the production of metal-D-gluconates
  • Fermentation process for the production of docosahexaneoic acid (DHA)
  • Microbial conversion of glucose to 2-ketogluconic acid as an intermediate for isovitamin C production
  • Kinetic resolution of (RS) naproxen using yeast
  • Kinetic resolution process for paroxetine drug intermediate (an anti depressant drug)