Mrs. Deepika Singh

Medicinal Chemistry Division
CSIR - Indian Institute of Integrative Medicine,Canal Road, Jammu – 180001
Email: dsingh@iiim.ac.in

Positions Held  
Position Held Date Organization
Senior Scientist 2013 - Present CSIR-IIIM
Scientist 2009 - 2013 CSIR-IIIM

Research

Microbial and marine Natural product chemistry.

  • Dereplication through Intact Cell Mass Spectrometry using Maldi Tof / Tof mass spectrometer to screen promising new bioactive peptides or peptaibols from the rich microbial biodiversity across the country, in particular to high altitudes and niche areas of the state and from the marine sources as well with novel drug discovery prospective.

  • Optimization of conditions for the maximal production of peptides or peptaibols by metabolic engineering of screened microbes through Maldi Tof Mass Spectrometer and the optimization of the extraction and purification method.

  • Identification and sequence determination of peptides and peptaibols through modern analytical techniques using Nuclear Magnetic Resonance and Mass spectrometer.

Publications
  • Kumar I; Panduga R; Mir N.A.; Singh, D; Gupta V; Rajnikant. Highly enantioselective [4+2] annulation via organocatalytic Mannich reductive cyclization: One pot Synthesis of functionalized pepridines. ChemComm (2013), 49, 5645-5647.

  • Singh, P.P.; Thatikonda, T; Kumar, A.; Sawant, S. D.; Singh, B.; Sharma, A. K.; Sharma, P.R.; Singh, D.; Vishwakarma, R. A. Cu-Mn Spinel Oxide Catalysed Regioselective halogenations of Phenols and N-Heteroarenes. Journal of Organic Chemistry (2012), 77, 5823-5828.

Patents:

  • Brachiatins D and process for their production thereof. Singh ,D.;Sharma, J. P.; Jaglan ,S.; Dar, A. H.;  Khajuria ,A.; Singh ,V. P.;Vishwakarma, R.A. (International/Indian Patent Application Filed 2563 DEL2013).