Dr. Bilal Ahmad Bhat

Medicinal Chemistry Division
CSIR - Indian Institute of Integrative Medicine,Canal Road, Jammu – 180001
Email: bilal@iiim.ac.in

Positions Held  
Position Held Date Organization
Scientist 2010 - Present CSIR-IIIM

Research

The science of organic synthesis deals with the creation of diverse molecular architectures through controlled, efficient and logically orchestrated carbon-carbon and carbon-heteroatom bond connectivities. This field of chemical science continues to be the most exciting, challenging and fascinating having rich history and vibrant future. Thus organic synthesis is a unique branch of science that blends art and aesthetics with creation and utility and our synthetic interests include:

  • Molecules of nature and human imagination

  • Total synthesis of bioactive natural products

  • New synthetic strategies for natural/non-natural product scaffolds

  • Regio-, stereo- and enantio-selective synthesis

Publications
  • Lone, A. M.; Bhat, B. A.; Mehta, G. A general, flexible, ring closing metathesis (RCM) based strategy for accessing the fused furo[3,2-b]furanone moiety present in diverse bioactive natural products. Tetrahedron Letters (2013), 54,5619-5623

  • Shairgojray, B. A.; Dar, A. A.; Bhat, B. A. Micellar promiscuity: An expeditious approach to Morita-Baylis-Hillman reaction. Tetrahedron Letters (2013), 54, 2391-2394

  • Rashid, S.; Dar, B. A.; Majeed, R.; Hamid, A.; Bhat, B. A. Synthesis and biological evaluation of ursolic acid-triazolyl derivatives as potential anti-cancer agents. European Journal of Medicinal Chemistry (2013) 66, 238-245

  • Mehta, G.; Bhat, B. A.; Kumara,S. T.H. Studies directed towards the synthesis of schisanartane and related complex nortriterpenoids: Construction of models of the peripheral ABC and FGH segments of rubrifloradilactone C. Tetrahedron Letters (2010), 51, 4069-4072

  • Mehta, G.; Bhat, B. A. Synthetic studies towards novel neurotrophic diterpenoids neovibsanins A & B: Construction of the ABC core. Tetrahedron Letters (2009), 50, 2474-2477

  • Mehta, G.; Bhat, B. A.; Kumara,S. T.H. An expeditious, bidirectional synthesis of furofuranones: New application of Morita-Baylis-Hillman adducts. Tetrahedron Letters (2009), 50, 6597-6600

  • Bhat, B. A.; Reddy, P. B.; Agrawal, S. K.; Saxena, A.K.; Kumar, H. M. S.; Qazi. G. N. Studies on 4b-[(4-substituted)-1,2,3-triazol-1-yl] podophyllotoxins as potential anticancer agents. European Journal of Medicinal Chemistry (2008) 43, 2067-2072

  • Bhat, B. A.; Shafi, S.; Purnima, B.; Banday, A. H.; Kumar. H. M. S. Ferrier Rearrangement of PEG-bound amino acids with D-Glucal to 2,3-unsaturated glycopyranisides. Tetrahedron Letters (2007), 48, 1041-1043

  • Bhat, B. A.; Dhar, K. L.; Puri, S.C.; Spiteller. M. A novel one-pot rearrangement reaction of 2,3-epoxydiaryl ketones: Synthesis of 5,5-disubstituted-imidazolones and 5,5-disubstituted-hydantoins. Synlett (2006), 17, 2723-2726.

  • Bhat, B. A.; Dhar, K. L.; Puri, S. C.; Saxena, A.K.; Shanmugavel, M.; Qaz.G.N. Synthesis and biological evaluation of chalcones and their derived pyrazoles as potential cytotoxic agents. Bioorganic & Medicinal Chemistry Letters (2005), 15, 3177-3180