Dr. Asha Chaubey

Fermentation Technology Divisionbr /> CSIR - Indian Institute of Integrative Medicine,Canal Road, Jammu – 180001
Email: achaubey@iiim.ac.in

Positions Held  
Position Held Date Organization
Sr.Scientist 2010 - Present CSIR-IIIM

Research

  • Isolation characterization of microorganisms including endophytes and extremophiles for novel bioactives/biocatalysts and their chemo profiling

  • Novel microbial enzymes of pharmaceutical importance specifically lipases, nitrilases and aldolases, biotransformations and kinetic resolution of drug/drug intermediates

  • Enzyme immobilization and enzymatic processes using free and immobilized enzymes

Publications
  • Yusuf, F.; Chaubey, A.; Jamwal, U.; Parshad,R. A new isolate from Fusarium proliferatum (AUF-2) for efficient nitrilase production. Applied Biochemistry and Biotechnology (2013), 171, 1022-1031

  • Yusuf,F.; Chaubey,A.; Raina,A.; Jamwal,U.; Parshad,R. Enhancing nitrilase production from Fusarium proliferatum using response surface methodology.  SpringerPlus (2013), 2, 290.

  • Chaubey, A.; Raina,C.; Parshad,R.; Rouf, A.; Gupta, P.; Taneja, S.C. Bioconversion of sucralose-6-acetate to sucralose using immobilized microbial enzymes. Journal of Molecular Catalysis B (2013), 91 81-86.

  • Chaubey, A.; Parshad, R.; Taneja, S.C.; Deokar, S.; Rajan, C.R.; Ponrathnam, S. Immobilization of enantioselective lipase on soluble supports for kinetic resolution of drug intermediates. Journal of Bioactive and Compatible Polymers (2012), 27, 499-509.

  • Felnagle, E.A.; Chaubey, A.; Noey, E.L.; Houk, K.N.; Liao, J.C. Engineering Synthetic Recursive Pathways. Nature Chemical Biology (2012),8, 518-526.

  • Marcheschi, R.J.; Zhang,K.; Noey, E.L.; Kim, S.; Li,H.; Chaubey,A.; Houk, K.N.; Liao,J.C. A Synthetic Recursive “+1” Pathway for Carbon Chain Elongation. ACS Chemical Biology, (2012), 7, 689–697

  • Chaubey,A.; Parshad, R.; Gupta, P. Taneja, S.C.; Qazi, G.N.; Rajan, C. R.; Ponrathnam, S. Arthrobacter  sp. lipase immobilization for preparation of enantiopure masked b-amino alcohols, Bioorganic & Medicinal Chemistry (2009), 17, 29-34.

  • Chaubey,A.; Parshad, R.; Koul,S.; Taneja, S.C.; Qazi, G.N. Arthrobacter   sp. lipase immobilization for improvement in stability and   enantioselectivity. Applied Microbiology and Biotechnology (2006), 73, 598–606.

  • Chaubey, A.; Malhotra,B.D. Mediated Biosensors, Biosensors & Bioelectronics (2002), 17, 441-456.

  • Gerard,M.; Chaubey, A.; Malhotra, B.D. Application of Conducting Polymers to Biosensors,  Biosensors & Bioelectronics (2002), 17, 345-359.

Patents

  • Lactate biosensing strip; Pandey,M.K.; Chaubey,A.; Pande, K.K.; Sharma, R.K.; Saini, K.K.; Malhotra, B.D. and Rajesh (CA 2512281).

  • Method for preparing lactate biosensing strip; Pandey,M.K.; Chaubey,A.; Pande, K.K.; Sharma, R.K.; Saini, K.K.; Malhotra, B.D. and Rajesh (CA 2512279).

  • Method for manufacture of lactate biosensing strip; Pandey,M.K.; Chaubey,A.; Pande, K.K.; Sharma, R.K.; Saini, K.K.; Malhotra, B.D. and Rajesh(United States Patent No 7364873)

  • Lactate biosensing strip with two electrodes; Pandey,M.K.; Chaubey,A.; Pande, K.K.; Sharma, R.K.; Saini, K.K.; Malhotra, B.D. and Rajesh (United States Patent No. 7,319,018)

  • Lactate biosensing strip; Pandey,M.K.; Chaubey,A.; Pande, K.K.; Sharma, R.K.; Saini, K.K.; Malhotra, B.D. and Rajesh(European  Patent No. EP 1 578 985 B1)

  • A novel conducting polymer based electrode for the estimation of cholesterol in aqueous solution; Kumar A., Chaubey, A.; Rajesh and Malhotra, B.D. (United States Patent No. Us 7,175,746 B2)

  • Process for the preparation of lactate biosensing strip useful for the preparation of lactate in aqueous solution. Pandey, M.K.; Chaubey, A.;  Pande,K.K., Rajesh, Sharma, R.K., Saini, K.K.; Malhotra, B.D. and Rajesh (Indian Patent No. 197458)